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Top 24 Hotels Near Center of Clayton
50 Gay Ave Clayton, MO 63105



Residence Inn by Marriott St. Louis Clayton

8125 Forsyth Blvd St. Louis, Missouri

From Residence Inn by Marriott St. Louis Clayton, Center of Clayton is an easy walk away, a detail that enhances the feeling of being well-situated.

Grab-and-go markets in Residence Inn receptions offer snacks and drinks immediately at arrival, reducing friction and signaling thoughtful care. Suites include ergonomic workspaces, task lighting, and Wi-Fi, giving business travelers practical setups that make productivity effortless. Shared atrium spaces with natural light, sofa clusters, and open layouts create orientation points while reinforcing welcoming impressions.

Business centers, self-parking, complimentary breakfast, indoor pools, and internet access maintain consistency during extended stays.

  Call (855) 235-6136 to book with an agent.
  0.5 miles from Center of Clayton

Starting at

$242.99

per night

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Hampton Inn & Suites Clayton / St. Louis-Galleria Area

216 North Meramec Ave St. Louis, Missouri

The hotel's location is a practical choice, with Center of Clayton a quick trip away, framing the stay around accessibility and ease.

Hampton Inn infused water setups inside lobbies demonstrate thoughtful details, giving arrivals refreshing pauses after long drives. Suites come with microwaves, mini-fridges, and coffee makers, offering dependable access to light meals and beverages within rooms. Lobby areas with community tables, sofas, and natural light create hubs that support relaxed interaction and group coordination easily.

Complimentary Wi-Fi, valet parking, indoor pools, breakfast buffets, and business lounges deliver convenience that supports each stay.

  Call (855) 234-2997 to book with an agent.
  0.9 miles from Center of Clayton

Starting at

$160.99

per night

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Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis, Missouri

Center of Clayton is a brief ride from Clayton Plaza Hotel & Extended Stay, a detail that ensures the journey there is as simple as the stay itself.

A professional and efficient check-in is the standard at Extended Stay America, where the staff understands the needs of travelers. The included cookware and utensils in every kitchen add a significant layer of convenience, making it easy to settle into the hotel room. The 24/7 accessibility of the guest laundry is a major benefit for guests with unconventional work schedules, such as night-shift workers.

Between the free grab-and-go breakfast, a fitness center, guest laundry, and a full kitchen, convenience is built into every stay.

  Call (855) 235-6136 to book with an agent.
  1.0 miles from Center of Clayton

Starting at

$108.99

per night

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Le Méridien St. Louis Clayton

7730 Bonhomme Ave St. Louis, Missouri

From Le Méridien St. Louis Clayton, Center of Clayton is an easy drive, a choice that makes for an uncomplicated and well-placed stay.

With Sparkling cocktail service in the lobby, Le Méridien reinforces heritage through a ritual that eases arrivals and adds refinement. Every suite presents hardwood floors, open wardrobes, and curated minibars, highlighting refined design paired with guest comfort. The spa features massage suites, aromatherapy rooms, and saunas, refreshing guests with rituals that restore energy and relaxation.

With breakfast spreads, cultural lounges, outdoor seating, and wellness spas, guests experience reliable amenities with daily ease.

  Call (855) 233-0132 to book with an agent.
  1.1 miles from Center of Clayton

Starting at

$191.99

per night

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The Ritz-Carlton St. Louis

100 Carondelet Plaza St. Louis, Missouri

The journey from The Ritz-Carlton St. Louis to Center of Clayton is a straightforward drive, a perk that contributes to an effortless visit.

Upon arrival, Ritz-Carlton associates provide sincere greetings, setting an inclusive tone that makes orientation clear and comfort immediate. Standard guest rooms pair smart TVs with streaming and casting, enabling easy entertainment choices without disrupting travel schedules. Fitness studios include Peloton bikes, stretching zones, and hydration points, letting routines remain consistent despite variable travel days.

With spa access, fitness rooms, and hydration points plus bar seating, travelers maintain routines and connect comfortably after events.

  Call (855) 234-2997 to book with an agent.
  1.5 miles from Center of Clayton

Starting at

$539.99

per night

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Homewood Suites by Hilton St. Louis - Galleria

8040 Clayton Road Richmond Heights, Missouri

In Clayton, Homewood Suites by Hilton St. Louis - Galleria is situated a quick drive from Center of Clayton, which lends value to the guest experience.

Soft lighting and residential furnishings define Homewood Suites lobbies, producing a calm tone that softens the move from travel. Each guest room provides bedside USB outlets, Wi-Fi, and ergonomic chairs, letting guests remain connected and productive easily. Business centers with computers, printers, and internet access keep travelers connected and productive during their hotel visits.

Parking options, business centers, complimentary Wi-Fi, and breakfast buffets help guests keep travel efficient and stress-free.

  Call (855) 234-7135 to book with an agent.
  1.5 miles from Center of Clayton

Starting at

$162.99

per night

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MainStay Suites St. Louis - Galleria

8011 Galleria Parkway Richmond Heights, Missouri

For guests in Clayton, MainStay Suites St. Louis - Galleria is an easy drive from Center of Clayton, a position that makes for a convenient and fast-paced visit.

When weather turns, MainStay Suites keeps entry runners and umbrella stands handy, preserving safe footing as bags are moved inside. Each guest room keeps a small dining table or counter, enabling quick meals, planning sessions, or device setups without crowding other areas. Fitness studios often pair cardio machines with stretching zones and hydration stations so training routines remain varied and reliable.

From kitchenette-equipped suites and in-room coffee to laundry access, free Wi-Fi, and expanded parking, longer stays stay practical and calm.

  Call (855) 236-8982 to book with an agent.
  2.0 miles from Center of Clayton

Starting at

$85.99

per night

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Courtyard by Marriott St. Louis Brentwood

8101 Dale Avenue Richmond Heights, Missouri

In Clayton, Courtyard by Marriott St. Louis Brentwood's accessible location to Center of Clayton lets guests commute with a sense of freedom.

Upon entry, Courtyard guests encounter floral displays, bright finishes, and polished counters, cues that provide clarity and comfort. Suites supply flexible layouts, sofa seating, and hardwood details, providing stylish comfort that remains consistent worldwide. At the Bistro, light meals, Starbucks® drinks, and soft seating balance productivity and relaxation for guests throughout the day.

Amenities such as business lounges, valet parking, breakfast service, and 24/7 markets sustain productivity and simplify routines.

  Call (855) 239-4019 to book with an agent.
  2.8 miles from Center of Clayton

Starting at

$161.99

per night

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TownePlace Suites by Marriott Brentwood

1695 SOUTH HANLEY ROAD Brentwood, Missouri

Center of Clayton is a quick drive from TownePlace Suites by Marriott Brentwood, a plan that ensures the commute itself is a pleasant one.

Something Borrowed® stations at TownePlace Suites offer practical items, showing thoughtful support that helps arrivals feel cared for instantly. Each guest room has smart TVs, refrigerators, and compact kitchenettes, helping travelers manage meals while enjoying downtime easily. Laundry facility offers coin exchanges and guide racks, helping routine chores sync with trip scheduling in a user-friendly manner.

Outdoor pool, business center, and mobile check-in offer leisure, productivity, and seamless access, keeping routines active without friction.

  Call (855) 234-5074 to book with an agent.
  3.1 miles from Center of Clayton

Starting at

$160.99

per night

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The Knight Center at Washington University

Throop Dr. and Snow Way St. Louis, Missouri

The quick drive from The Knight Center at Washington University to Center of Clayton in Clayton means guests have a reliable way to arrive without confusion.

Guests at The Knight Center at Washington University may encounter basic front desk help, self-serve coffee, and parking close to the lobby for predictable arrivals. Each guest room may include hardwood accents, comfortable bedding, and complimentary Wi-Fi, helping guests maintain comfort and connection. Shared spaces may include vending areas, compact seating, and breakfast counters that emphasize the straightforward style of budget travel.

A visit may present Wi-Fi, modest breakfast, laundry facilities, and vending corners, creating functional balance for traveling guests.

  Call (855) 233-0132 to book with an agent.
  3.2 miles from Center of Clayton

Starting at

$169.99

per night

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SpringHill Suites St. Louis Brentwood

1231 Strassner Drive Brentwood, Missouri

The hotel's spot a short drive from Center of Clayton gives SpringHill Suites St. Louis Brentwood guests a simple way to start their day.

With Digital Key access and complimentary Wi-Fi, SpringHill Suites ensures frequent travelers begin smoothly, avoiding friction at arrival. Suites are equipped with microwaves, compact fridges, and coffee machines, supporting convenience for both long-term travelers and short visits. The business center highlights computers, fax access, and ergonomic chairs, supporting professionals who need continuity during their travels.

Complimentary Wi-Fi, hot breakfast with Rainforest Alliance coffee, fitness center access, and indoor pools combine to keep routines balanced.

  Call (855) 233-0132 to book with an agent.
  3.3 miles from Center of Clayton

Starting at

$136.99

per night

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The Cheshire

6300 Clayton Rd Richmond Heights, Missouri

Reaching Center of Clayton from The Cheshire is a simple drive, a trait that enhances the overall guest experience with simplicity.

The Cheshire often greets guests with polished interiors, courteous staff, and refined seating that establish a sophisticated welcome. Accommodations typically include upscale décor, premium linens, and spa-style bathrooms that may feature refined luxury finishes. Property amenities often offer stylish bars, full-service dining, and wellness spaces designed to enhance a luxury-focused impression.

Accommodations may highlight stylish interiors, wellness areas, valet services, and Wi-Fi, blending polished comfort with convenience.

  Call (855) 234-2997 to book with an agent.
  4.1 miles from Center of Clayton

Starting at

$141.99

per night

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Moonrise Hotel

6177 Delmar Blvd St. Louis, Missouri

Within Clayton, Moonrise Hotel is a quick drive from Center of Clayton, a fact that lets the hotel to feel both convenient and accessible.

Arrivals at Moonrise Hotel typically showcase professional luggage assistance, elegant décor, and polished reception for a luxury introduction. Rooms may offer spacious seating, elegant décor, and in-room coffee or tea service for a refined and comfortable luxury experience. Facilities may include refined lounges, spa-inspired services, and elegant dining options that contribute to a polished guest experience.

Guests may encounter premium bedding, spa facilities, cocktail bars, and Wi-Fi, reinforcing balance in both leisure and productivity.

  Call (855) 234-5074 to book with an agent.
  4.3 miles from Center of Clayton

Starting at

$130.99

per night

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Hilton St. Louis Frontenac

1335 South Lindbergh Blvd Frontenac, Missouri

From Hilton St. Louis Frontenac, the simple automotive access to Center of Clayton is a welcome feature to the destination for travelers.

Hilton situates its concierge desks and visible signage at arrival, giving travelers confidence and orientation clarity instantly. Guest rooms include Wi-Fi, smart TVs, and bedside charging stations, supporting entertainment and connectivity during every stay. At the breakfast lounge, hot items, pastries, and coffee provide guests with routines that ensure mornings begin smoothly and clearly.

Amenities include valet parking, breakfast buffets, indoor pools, and meeting rooms, giving guests balance between work and leisure.

  Call (855) 233-0132 to book with an agent.
  5.4 miles from Center of Clayton

Starting at

$162.99

per night

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Hampton Inn & Suites St. Louis at Forest Park

5650 Oakland Avenue St. Louis, Missouri

When visiting Center of Clayton in Clayton, the drive from Hampton Inn & Suites St. Louis at Forest Park is an easy drive, allowing for a quick return to the hotel.

Digital check-in tools in Hampton Inn receptions ensure loyalty members experience smoother arrivals with dependable recognition. All guest rooms contain blackout drapes, premium bedding, and thermostats, producing restful environments that support restorative sleep. Business lounges with desks, copy machines, and reliable internet ensure travelers stay productive, providing consistent workspaces.

Pet-friendly options, complimentary breakfast, Pavilion Pantry counters, fitness rooms, and Wi-Fi connectivity ensure comfort and ease.

  Call (855) 239-5277 to book with an agent.
  6.3 miles from Center of Clayton

Starting at

$136.99

per night

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Forest Park Hotel by MDR

5915 Wilson Ave St. Louis, Missouri

The journey from Forest Park Hotel by MDR to Center of Clayton is an uncomplicated drive, a benefit that helps frame a convenient and well-organized stay.

Guests at Forest Park Hotel by MDR may encounter artisanal coffee, curated décor, and boutique reception touches that emphasize a personal experience. Guest rooms typically showcase stylish interiors, artisanal touches, and bathrooms with polished finishes for a refined impression. Facilities may showcase locally sourced dining, curated lounges, and stylish bars for a polished boutique guest impression.

A visit may present Wi-Fi, artisanal breakfast, laundry support, and bike rentals, sustaining boutique practicality during travel.

  Call (855) 239-4019 to book with an agent.
  6.5 miles from Center of Clayton

Starting at

$79.99

per night

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Red Roof Inn PLUS+ St. Louis - Forest Park / Hampton Ave

5823 Wilson Avenue St. Louis, Missouri

For a stay that depends on reliable car travel, Red Roof Inn PLUS+ St. Louis - Forest Park / Hampton Ave offers a direct run to Center of Clayton, making it a solid foundation for your trip.

The bright lighting and open sightlines in Red Roof Inn lobbies contribute to a safe environment, particularly for solo or family travelers. Each guest room includes a telephone with free local calls, a useful feature for making reservations or contacting nearby businesses. A dedicated business kiosk in the lobby includes a computer and printer, allowing guests to manage essential work tasks efficiently.

A practical suite of amenities, including free parking, laundry, a pool, and free Wi-Fi, helps guests stick to their budget and routine.

  Call (855) 235-0725 to book with an agent.
  6.6 miles from Center of Clayton

Starting at

$71.99

per night

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The Royal Sonesta Chase Park Plaza St. Louis

212 North Kingshighway St. Louis, Missouri

When a trip to Clayton involves multiple stops, The Royal Sonesta Chase Park Plaza St. Louis's location an easy drive from Center of Clayton is a useful asset.

Royal Sonesta orients elevators just off the desk line, reducing bottlenecks at the counter and speeding the handoff from check-in to room. Each suite enhances lighting with task and ambient layers, improving screen visibility for work while keeping evenings relaxed. The pool deck positions loungers and shade elements near towel pickup, setting up effortless transitions between swim and rest.

Between breakfast areas, coffee points, and grab-and-go shelves, early departures get fueled without delaying check-out or shuttles.

  Call (855) 234-5074 to book with an agent.
  7.3 miles from Center of Clayton

Starting at

$131.99

per night

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AC Hotel St. Louis Central West End

215 YORK AVENUE St. Louis, Missouri

The benefit of a simple drive to Center of Clayton makes AC Hotel St. Louis Central West End into a great hub before the main experience begins.

Lobbies at AC Hotels highlight neutral palettes, natural light, and curated art pieces, projecting dependable elegance and refined first impressions. All guest rooms provide mini-fridges, coffee stations, and bottled water, making routines simple for both families and business travelers daily. Meeting areas combine natural light, ergonomic furniture, and AV access, enabling reliable productivity for both corporate and social events.

Daily routines are supported by free Wi-Fi, AC Kitchen croissants, AC Lounge cocktails, and meeting rooms, offering clarity and predictable ease.

  Call (855) 239-4019 to book with an agent.
  7.5 miles from Center of Clayton

Starting at

$200.99

per night

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DoubleTree by Hilton St. Louis Forest Park

4550 Forest Park Ave St. Louis, Missouri

The benefit of having Center of Clayton within easy reach turns DoubleTree by Hilton St. Louis Forest Park into a great starting point for any visit.

DoubleTree’s complimentary cafe taps and signature cookie layer hospitality touches that provide ease and familiarity from the front door. Guest rooms supply complimentary Wi-Fi and charging hubs, ensuring seamless connectivity and consistent access to personal or work devices. Business centers with copy equipment and reliable Wi-Fi deliver productivity support, enabling travelers to complete tasks smoothly.

Free Wi-Fi, buffet breakfast, meeting spaces, valet, and transport support create clarity and balance for both business and leisure.

  Call (855) 234-7135 to book with an agent.
  7.6 miles from Center of Clayton

Starting at

$172.99

per night

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Hotel Indigo St. Louis - Central West End by IHG

4630 Lindell Boulevard Saint Louis, Missouri

This direct drive to Center of Clayton helps Hotel Indigo St. Louis - Central West End by IHG guests become more connected to the Clayton area.

Hotel Indigo greets travelers with complimentary coffee stations in eclectic lobbies, providing small courtesy touches that ease arrivals. Each guest room supplies flat-screen HDTVs, plush bedding, and blackout shades, balancing entertainment, rest, and daily comfort. Breakfast dining rooms with buffets, cereals, and coffee setups help families and professionals begin mornings with clarity.

Pet-friendly rooms, Wi-Fi, and boutique dining join with parking and pools, making stays flexible for both family and business guests.

  Call (855) 236-8982 to book with an agent.
  7.8 miles from Center of Clayton

Starting at

$145.99

per night

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Home2 Suites by Hilton St. Louis / Forest Park

920 South Taylor Avenue St. Louis, Missouri

Because Home2 Suites by Hilton St. Louis / Forest Park keeps Center of Clayton within easy reach, guests can decide to get there quickly and without hassle.

In Home2 Suites spaces, bright finishes, playful décor, and flexible seating establish a welcoming environment that feels consistent. Suites present sofa beds, smart TVs, and dining areas, offering convenience and flexibility for relaxation or casual gatherings. At the Oasis lobby, sofas, armchairs, and bright finishes create a comfortable area where colleagues or families can regroup casually.

With 24/7 markets, complimentary breakfast, business centers, and pools, travelers find a balance of productivity and relaxation.

  Call (855) 236-8982 to book with an agent.
  7.9 miles from Center of Clayton

Starting at

$175.99

per night

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Super 8 by Wyndham St. Louis Airport

9798 St. Charles Rock Rd St. Louis, Missouri

The hotel's spot a simple drive to Center of Clayton gives Super 8 by Wyndham St. Louis Airport guests a simple way to transition into their day.

Super 8 breakfast counters near reception create clarity for day-start routines, helping families and professionals begin smoothly. Guest rooms highlight ergonomic desks, strong Wi-Fi, and ample outlets, ensuring productivity and balance during professional trips. Pools with towel racks, loungers, and family seating deliver dependable leisure areas where guests can relax or recharge daily.

Complimentary breakfast, free Wi-Fi, and laundry connect with vending and pools, ensuring comfort for extended stays at each property.

  Call (855) 233-7850 to book with an agent.
  8.1 miles from Center of Clayton

Starting at

$64.99

per night

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Hilton Garden Inn St. Louis Airport

4450 Evans Place St. Louis, Missouri

From the lobby of Hilton Garden Inn St. Louis Airport, Center of Clayton is an easy drive with no stress, simplifying your visit.

Community tables in Hilton Garden Inn receptions act as flexible hubs, creating shared spaces where groups can organize plans together. Guest rooms provide rainfall showers, premium bath amenities, and soft towels, giving guests comfort and clarity during refresh routines. Breakfast areas with pastries, coffee stations, and hot buffets create reliable clarity that helps mornings begin smoothly every day.

Concierge services, complimentary breakfast, outdoor pools, Wi-Fi, and fitness studios simplify travel while enhancing everyday balance.

  Call (855) 236-8982 to book with an agent.
  8.3 miles from Center of Clayton

Starting at

$136.99

per night

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