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Top 24 Hotels Near Center of Clayton
50 Gay Ave Clayton, MO 63105

Residence Inn by Marriott St. Louis Clayton

8125 Forsyth Blvd St. Louis, Missouri

From Residence Inn by Marriott St. Louis Clayton, Center of Clayton is an easy walk away, a detail that enhances the feeling of being well-situated.

Grab-and-go markets in Residence Inn receptions offer snacks and drinks immediately at arrival, reducing friction and signaling thoughtful care. Suites include ergonomic workspaces, task lighting, and Wi-Fi, giving business travelers practical setups that make productivity effortless. Shared atrium spaces with natural light, sofa clusters, and open layouts create orientation points while reinforcing welcoming impressions.

Business centers, self-parking, complimentary breakfast, indoor pools, and internet access maintain consistency during extended stays.

  Call (855) 234-7135 to book with an agent.
  0.5 miles from Center of Clayton

Starting at

$239.99

per night

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Seven Gables St. Louis West, a Tribute Portfolio Hotel

26 North Meramec Avenue St. Louis, Missouri

The hotel is a brief trip from Center of Clayton, making the commute uncomplicated for guests.

Tribute Portfolio greets arrivals with locally inspired welcome drinks or snacks, rituals that reflect neighborhood identity and ease arrivals. Guest rooms provide ergonomic desks, Wi-Fi access, and bedside charging, giving professionals reliable setups for productivity. In the rooftop bar, cocktails, lighting, and lounge seating combine to create premium hubs that balance social connection and style.

Guests enjoy rooftop bars, spa treatments, breakfast buffets, and fitness centers, ensuring balance and convenience during stays.

  Call (855) 239-4019 to book with an agent.
  0.7 miles from Center of Clayton

Starting at

$201.99

per night

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Hampton Inn & Suites Clayton / St. Louis-Galleria Area

216 North Meramec Ave St. Louis, Missouri

The hotel's location is a practical choice, with Center of Clayton a quick trip away, framing the stay around accessibility and ease.

Hampton Inn infused water setups inside lobbies demonstrate thoughtful details, giving arrivals refreshing pauses after long drives. Suites come with microwaves, mini-fridges, and coffee makers, offering dependable access to light meals and beverages within rooms. Lobby areas with community tables, sofas, and natural light create hubs that support relaxed interaction and group coordination easily.

Complimentary Wi-Fi, valet parking, indoor pools, breakfast buffets, and business lounges deliver convenience that supports each stay.

  Call (855) 233-7850 to book with an agent.
  0.9 miles from Center of Clayton

Starting at

$190.99

per night

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AC Hotel St. Louis Clayton

227 South Central Ave St. Louis, Missouri

This adaptable location relative to Center of Clayton helps AC Hotel St. Louis Clayton guests get oriented and comfortable in the Clayton area.

Lobbies at AC Hotels highlight neutral palettes, natural light, and curated art pieces, projecting dependable elegance and refined first impressions. All guest rooms provide mini-fridges, coffee stations, and bottled water, making routines simple for both families and business travelers daily. Meeting areas combine natural light, ergonomic furniture, and AV access, enabling reliable productivity for both corporate and social events.

Daily routines are supported by free Wi-Fi, AC Kitchen croissants, AC Lounge cocktails, and meeting rooms, offering clarity and predictable ease.

  Call (855) 233-0132 to book with an agent.
  0.9 miles from Center of Clayton

Starting at

$219.99

per night

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Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis, Missouri

Center of Clayton is a brief ride from Clayton Plaza Hotel & Extended Stay, a detail that ensures the journey there is as simple as the stay itself.

A professional and efficient check-in is the standard at Extended Stay America, where the staff understands the needs of travelers. The included cookware and utensils in every kitchen add a significant layer of convenience, making it easy to settle into the hotel room. The 24/7 accessibility of the guest laundry is a major benefit for guests with unconventional work schedules, such as night-shift workers.

Between the free grab-and-go breakfast, a fitness center, guest laundry, and a full kitchen, convenience is built into every stay.

  Call (855) 233-7850 to book with an agent.
  1.0 miles from Center of Clayton

Starting at

$128.99

per night

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Le Méridien St. Louis Clayton

7730 Bonhomme Ave St. Louis, Missouri

From Le Méridien St. Louis Clayton, Center of Clayton is an easy drive, a choice that makes for an uncomplicated and well-placed stay.

With Sparkling cocktail service in the lobby, Le Méridien reinforces heritage through a ritual that eases arrivals and adds refinement. Every suite presents hardwood floors, open wardrobes, and curated minibars, highlighting refined design paired with guest comfort. The spa features massage suites, aromatherapy rooms, and saunas, refreshing guests with rituals that restore energy and relaxation.

With breakfast spreads, cultural lounges, outdoor seating, and wellness spas, guests experience reliable amenities with daily ease.

  Call (855) 233-7850 to book with an agent.
  1.1 miles from Center of Clayton

Starting at

$279.99

per night

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The Ritz-Carlton St. Louis

100 Carondelet Plaza St. Louis, Missouri

The journey from The Ritz-Carlton St. Louis to Center of Clayton is a straightforward hop, a perk that contributes to an effortless visit.

Upon arrival, Ritz-Carlton associates provide sincere greetings, setting an inclusive tone that makes orientation clear and comfort immediate. Standard guest rooms pair smart TVs with streaming and casting, enabling easy entertainment choices without disrupting travel schedules. Fitness studios include Peloton bikes, stretching zones, and hydration points, letting routines remain consistent despite variable travel days.

With spa access, fitness rooms, and hydration points plus bar seating, travelers maintain routines and connect comfortably after events.

  Call (855) 233-0132 to book with an agent.
  1.5 miles from Center of Clayton

Starting at

$719.99

per night

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Homewood Suites by Hilton St. Louis - Galleria

8040 Clayton Road Richmond Heights, Missouri

In Clayton, Homewood Suites by Hilton St. Louis - Galleria is situated a quick drive from Center of Clayton, which lends value to the guest experience.

Soft lighting and residential furnishings define Homewood Suites lobbies, producing a calm tone that softens the move from travel. Each guest room provides bedside USB outlets, Wi-Fi, and ergonomic chairs, letting guests remain connected and productive easily. Business centers with computers, printers, and internet access keep travelers connected and productive during their hotel visits.

Parking options, business centers, complimentary Wi-Fi, and breakfast buffets help guests keep travel efficient and stress-free.

  Call (855) 234-7135 to book with an agent.
  1.5 miles from Center of Clayton

Starting at

$188.99

per night

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MainStay Suites St. Louis - Galleria

8011 Galleria Parkway Richmond Heights, Missouri

For guests in Clayton, MainStay Suites St. Louis - Galleria is an easy drive from Center of Clayton, a position that makes for a convenient and fast-paced visit.

When weather turns, MainStay Suites keeps entry runners and umbrella stands handy, preserving safe footing as bags are moved inside. Each guest room keeps a small dining table or counter, enabling quick meals, planning sessions, or device setups without crowding other areas. Fitness studios often pair cardio machines with stretching zones and hydration stations so training routines remain varied and reliable.

From kitchenette-equipped suites and in-room coffee to laundry access, free Wi-Fi, and expanded parking, longer stays stay practical and calm.

  Call (855) 234-2997 to book with an agent.
  2.0 miles from Center of Clayton

Starting at

$115.99

per night

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Drury Inn & Suites St. Louis Brentwood

8700 Eager Rd Brentwood, Missouri

Because Drury Inn & Suites St. Louis Brentwood is a simple drive from Center of Clayton, guests can utilize a low-key journey before their day begins.

At arrival, Drury sets up convenience through lobby seating, concierge assistance, and efficient processes, offering clarity and immediate comfort. Each guest room includes safes, USB charging ports, and ergonomic desks, enabling secure storage and dependable productivity during travel. Conference rooms include projection screens, modular tables, and wired connections, helping groups coordinate effective gatherings seamlessly.

Guests can enjoy parking, free Wi-Fi, fitness zones, hot breakfast, business resources, and indoor pools, aligning ease with reliability each stay.

  Call (855) 234-2997 to book with an agent.
  2.5 miles from Center of Clayton

Starting at

$146.99

per night

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Courtyard by Marriott St. Louis Brentwood

8101 Dale Avenue Richmond Heights, Missouri

In Clayton, Courtyard by Marriott St. Louis Brentwood's accessible location to Center of Clayton lets guests commute with a sense of freedom.

Upon entry, Courtyard guests encounter floral displays, bright finishes, and polished counters, cues that provide clarity and comfort. Suites supply flexible layouts, sofa seating, and hardwood details, providing stylish comfort that remains consistent worldwide. At the Bistro, light meals, Starbucks® drinks, and soft seating balance productivity and relaxation for guests throughout the day.

Amenities such as business lounges, valet parking, breakfast service, and 24/7 markets sustain productivity and simplify routines.

  Call (855) 233-0132 to book with an agent.
  2.8 miles from Center of Clayton

Starting at

$134.99

per night

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TownePlace Suites by Marriott Brentwood

1695 SOUTH HANLEY ROAD Brentwood, Missouri

Center of Clayton is a quick drive from TownePlace Suites by Marriott Brentwood, a plan that ensures the commute itself is a pleasant one.

Something Borrowed® stations at TownePlace Suites offer practical items, showing thoughtful support that helps arrivals feel cared for instantly. Each guest room has smart TVs, refrigerators, and compact kitchenettes, helping travelers manage meals while enjoying downtime easily. Laundry facility offers coin exchanges and guide racks, helping routine chores sync with trip scheduling in a user-friendly manner.

Outdoor pool, business center, and mobile check-in offer leisure, productivity, and seamless access, keeping routines active without friction.

  Call (855) 233-0132 to book with an agent.
  3.1 miles from Center of Clayton

Starting at

$179.99

per night

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The Knight Center at Washington University

Throop Dr. and Snow Way St. Louis, Missouri

The quick drive from The Knight Center at Washington University to Center of Clayton in Clayton means guests have a reliable way to arrive without confusion.

Guests at The Knight Center at Washington University may encounter basic front desk help, self-serve coffee, and parking close to the lobby for predictable arrivals. Each guest room may include hardwood accents, comfortable bedding, and complimentary Wi-Fi, helping guests maintain comfort and connection. Shared spaces may include vending areas, compact seating, and breakfast counters that emphasize the straightforward style of budget travel.

A visit may present Wi-Fi, modest breakfast, laundry facilities, and vending corners, creating functional balance for traveling guests.

  Call (855) 233-0132 to book with an agent.
  3.2 miles from Center of Clayton

Starting at

$199.99

per night

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Charles F. Knight Executive Education Center

1197 Throop Drive St Louis, Missouri

The benefit of a simple drive to Center of Clayton renders Charles F. Knight Executive Education Center into a starting point for a day of easy transitions.

Charles F. Knight Executive Education Center typically provides quick desk service, modest lobby space, and complimentary parking that sustain easy travel routines. Rooms typically highlight simple seating, curated décor, and in-room coffee that may provide a reliable sense of comfort during travel. Facilities often feature guest laundries, modest lobbies, and vending machines that help maintain consistent routines for all visitors.

Guests may enjoy Wi-Fi, compact breakfast service, vending access, and laundry support, maintaining reliable daily routines away from home.

  Call (855) 234-5074 to book with an agent.
  3.2 miles from Center of Clayton

Starting at

$219.99

per night

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SpringHill Suites St. Louis Brentwood

1231 Strassner Drive Brentwood, Missouri

The hotel's spot a short drive from Center of Clayton gives SpringHill Suites St. Louis Brentwood guests a simple way to start their day.

With Digital Key access and complimentary Wi-Fi, SpringHill Suites ensures frequent travelers begin smoothly, avoiding friction at arrival. Suites are equipped with microwaves, compact fridges, and coffee machines, supporting convenience for both long-term travelers and short visits. The business center highlights computers, fax access, and ergonomic chairs, supporting professionals who need continuity during their travels.

Complimentary Wi-Fi, hot breakfast with Rainforest Alliance coffee, fitness center access, and indoor pools combine to keep routines balanced.

  Call (855) 234-2997 to book with an agent.
  3.3 miles from Center of Clayton

Starting at

$151.99

per night

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The Cheshire

6300 Clayton Rd Richmond Heights, Missouri

Reaching Center of Clayton from The Cheshire is a simple drive, a trait that enhances the overall guest experience with simplicity.

The Cheshire often greets guests with polished interiors, courteous staff, and refined seating that establish a sophisticated welcome. Accommodations typically include upscale décor, premium linens, and spa-style bathrooms that may feature refined luxury finishes. Property amenities often offer stylish bars, full-service dining, and wellness spaces designed to enhance a luxury-focused impression.

Accommodations may highlight stylish interiors, wellness areas, valet services, and Wi-Fi, blending polished comfort with convenience.

  Call (855) 234-7135 to book with an agent.
  4.1 miles from Center of Clayton

Starting at

$134.99

per night

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Moonrise Hotel

6177 Delmar Blvd St. Louis, Missouri

Within Clayton, Moonrise Hotel is a quick drive from Center of Clayton, a fact that lets the hotel to feel both convenient and accessible.

Arrivals at Moonrise Hotel typically showcase professional luggage assistance, elegant décor, and polished reception for a luxury introduction. Rooms may offer spacious seating, elegant décor, and in-room coffee or tea service for a refined and comfortable luxury experience. Facilities may include refined lounges, spa-inspired services, and elegant dining options that contribute to a polished guest experience.

Guests may encounter premium bedding, spa facilities, cocktail bars, and Wi-Fi, reinforcing balance in both leisure and productivity.

  Call (855) 235-6136 to book with an agent.
  4.3 miles from Center of Clayton

Starting at

$152.99

per night

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Hilton St. Louis Frontenac

1335 South Lindbergh Blvd Frontenac, Missouri

From Hilton St. Louis Frontenac, the direct automotive access to Center of Clayton is a welcome featureto the venue for travelers.

Hilton situates its concierge desks and visible signage at arrival, giving travelers confidence and orientation clarity instantly. Guest rooms include Wi-Fi, smart TVs, and bedside charging stations, supporting entertainment and connectivity during every stay. At the breakfast lounge, hot items, pastries, and coffee provide guests with routines that ensure mornings begin smoothly and clearly.

Amenities include valet parking, breakfast buffets, indoor pools, and meeting rooms, giving guests balance between work and leisure.

  Call (855) 235-0725 to book with an agent.
  5.4 miles from Center of Clayton

Starting at

$175.99

per night

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Drury Plaza Hotel St. Louis Creve Coeur

11980 Olive Blvd St. Louis, Missouri

When staying in Clayton, the uncomplicated drive from Drury Plaza Hotel St. Louis Creve Coeur to Center of Clayton is a simple drive, allowing for a low-stress start to the day.

Check-in at Drury Plaza Hotel is often followed by orientation materials or verbal guidance, helping guests understand available perks. Suites highlight private living rooms, multiple televisions, and sectional seating, giving guests the space to both gather and rest. Quiet corners or reading nooks include ambient lighting, upholstered chairs, side tables, and books or magazines for low‑stimulus repose.

From meeting rooms and valet support to widespread Wi‑Fi, the full setup streamlines transitions, productivity, and daily movement.

  Call (855) 233-0132 to book with an agent.
  5.5 miles from Center of Clayton

Starting at

$159.99

per night

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Drury Inn & Suites St. Louis Airport

10490 Natural Bridge Rd St. Louis, Missouri

For guests in Clayton, Drury Inn & Suites St. Louis Airport keeps Center of Clayton a simple cross-town drive, a location that supports a relaxed and easy schedule.

Drury staff emphasize routine hospitality—welcoming gestures, quick service, and breakfast cues that prepare guests for smooth mornings. Suites showcase family-friendly features—sofa sleepers, multiple TVs, and compact fridges—helping parents balance comfort and practicality. Lobbies with seating zones, natural light, and Wi-Fi access encourage relaxed conversation and productive transitions between outings.

With shuttle services, breakfast areas, pet support, Wi-Fi, business centers, and laundry, guests benefit from organized care across trip demands.

  Call (855) 234-2997 to book with an agent.
  6.1 miles from Center of Clayton

Starting at

$115.99

per night

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Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann, Missouri

From the moment you arrive at Pear Tree Inn St. Louis Airport, Center of Clayton is an easy drive, making for an easy start.

Arrivals at Pear Tree Inn St. Louis Airport may feature vending access, efficient reception, and accessible parking to reinforce guest convenience. Accommodations may feature compact layouts, functional desks, and streaming access, supporting productivity and relaxation throughout the stay. Public areas typically present vending access, compact business corners, and breakfast rooms that reinforce functional guest routines.

A stay often features Wi-Fi, guest laundry, vending machines, and modest breakfast, sustaining clarity and convenience for travelers.

  Call (855) 234-5074 to book with an agent.
  6.1 miles from Center of Clayton

Starting at

$97.99

per night

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Hampton Inn & Suites St. Louis at Forest Park

5650 Oakland Avenue St. Louis, Missouri

When visiting Center of Clayton in Clayton, the drive from Hampton Inn & Suites St. Louis at Forest Park is an easy drive, allowing for a quick return to the hotel.

Digital check-in tools in Hampton Inn receptions ensure loyalty members experience smoother arrivals with dependable recognition. All guest rooms contain blackout drapes, premium bedding, and thermostats, producing restful environments that support restorative sleep. Business lounges with desks, copy machines, and reliable internet ensure travelers stay productive, providing consistent workspaces.

Pet-friendly options, complimentary breakfast, Pavilion Pantry counters, fitness rooms, and Wi-Fi connectivity ensure comfort and ease.

  Call (855) 236-8982 to book with an agent.
  6.3 miles from Center of Clayton

Starting at

$143.99

per night

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Drury Inn & Suites St. Louis Forest Park

2111 Sulphur Avenue St. Louis, Missouri

Because Drury Inn & Suites St. Louis Forest Park keeps Center of Clayton a simple drive, guests can appreciate a low-key journey before their day begins.

From reception forward, Drury maintains clarity with early luggage help, friendly staff, and evening Kickback® anticipation woven into service. Guest rooms provide mini-fridges, microwaves, and coffee makers, ensuring travelers maintain personal refreshment at any time of day. Fitness rooms offer free weights, cardio machines, and yoga mats, letting health-conscious travelers maintain regular fitness practices daily.

From meeting spaces, pools, Kickback® snacks, Wi-Fi, parking, and laundry, travelers receive balanced amenities tailored to everyday routines.

  Call (855) 234-2997 to book with an agent.
  6.4 miles from Center of Clayton

Starting at

$124.99

per night

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Forest Park Hotel by MDR

5915 Wilson Ave St. Louis, Missouri

The journey from Forest Park Hotel by MDR to Center of Clayton is an uncomplicated drive, a benefit that helps frame a convenient and well-organized stay.

Guests at Forest Park Hotel by MDR may encounter artisanal coffee, curated décor, and boutique reception touches that emphasize a personal experience. Guest rooms typically showcase stylish interiors, artisanal touches, and bathrooms with polished finishes for a refined impression. Facilities may showcase locally sourced dining, curated lounges, and stylish bars for a polished boutique guest impression.

A visit may present Wi-Fi, artisanal breakfast, laundry support, and bike rentals, sustaining boutique practicality during travel.

  Call (855) 234-2997 to book with an agent.
  6.5 miles from Center of Clayton

Starting at

$102.99

per night

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