The best deals on hotels near Center ST. Louis in Affton, MO.

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Top 24 Hotels Near Center ST. Louis
6727 Langley Ave Affton, MO 95843



Days Inn by Wyndham St. Louis Lindbergh Boulevard

3654 South Lindbergh Blvd ST. LOUIS, Missouri

The guest's journey from Days Inn by Wyndham St. Louis Lindbergh Boulevard in Affton to Center ST. Louis is a quick drive, enhancing the sense of being in a convenient location.

Desk counters at Days Inn include a low-height segment, keeping paperwork comfortable while the path to elevators stays unobstructed. All guest rooms add a chair by the window for reading, while window coverings temper glare so downtime stays relaxed and comfortable. Pool decks use non-slip surfaces and posted hours with clear rules, setting expectations for quiet periods and tidy wrap-ups.

Pool access where offered plus lounge chairs, posted hours, and Wi-Fi shapes calm breaks with easy returns to elevators afterward.

  Call (855) 234-5074 to book with an agent.
  4.1 miles from Center ST. Louis

Starting at

$131.99

per night

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Americas Best Value Inn St. Louis South

6602 South Lindbergh Blvd St. Louis, Missouri

The benefit of a uncomplicated drive to Center ST. Louis turns Americas Best Value Inn St. Louis South into a great starting point before the rest of the stay unfolds.

With visible bell or attendant presence Americas Best Value Inn streamlines luggage handoffs so guests proceed to rooms without hassle. Standard guest rooms feature blackout drapes, quiet HVAC, and supportive mattresses to encourage restorative sleep after long travel days. Lobby seating often places charging ports and small tables so companions can charge devices and plan next steps while waiting at the desk.

From laundry and dry-cleaning to meeting support and Wi-Fi, longer stays keep wardrobes ready while work remains connected and efficient, and stay on schedule.

  Call (855) 234-7135 to book with an agent.
  5.7 miles from Center ST. Louis

Starting at

$72.99

per night

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River City Casino & Hotel

777 River City Casino Blvd St. Louis, Missouri

The journey from River City Casino & Hotel to Center ST. Louis is an easy drive, an asset that adds flexibility to any driving itinerary.

At River City Casino & Hotel, arrivals may feature professional doorman presence, stylish interiors, and polished staff shaping a refined first impression. Accommodations may include upscale décor, plush bedding, and spa-style bathrooms that highlight a polished and comfortable retreat. Property amenities often showcase fine dining, stylish cocktail lounges, and spa services that reflect a polished and refined retreat.

Guests may encounter premium bedding, rooftop lounges, spa facilities, and Wi-Fi, combining digital ease with upscale relaxation.

  Call (855) 233-7850 to book with an agent.
  6.7 miles from Center ST. Louis

Starting at

$85.99

per night

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Comfort Suites St. Louis - Sunset Hills

3654 South LINDBERGH BLVD St. Louis, Missouri

Within Affton, Comfort Suites St. Louis - Sunset Hills keeps Center ST. Louis within easy reach, which helps the hotel to feel both convenient and calm.

Comfort Suites arrival areas include vending or market shelves beside reception to supply late-night snacks, drinks, and essentials. Each guest room offers blackout drapes, supportive mattresses, and quiet HVAC to promote restorative sleep and steadier mornings on the road. Bar areas and cafés produce quick plates, espresso, and casual seating to anchor meet-ups before evening plans without a long wait.

With free Wi-Fi, meeting rooms, and simple AV hookups, small teams can host briefings and keep agendas on schedule without extra vendors.

  Call (855) 234-5074 to book with an agent.
  6.7 miles from Center ST. Louis

Starting at

$117.99

per night

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Best Western St. Louis-Kirkwood Route 66

1200 South Kirkwood Road Kirkwood, Missouri

The hotel's spot an uncomplicated drive from Center ST. Louis gives Best Western St. Louis-Kirkwood Route 66 guests a easy option for their daily commute.

Best Western situates a concierge information nook near café counters, letting companions pause with refreshments while requests are organized. All guest rooms can provide ADA-aligned layouts where booked—grab bars or roll-in configurations—supporting accessible, confident stays. Outdoor pools where available add shade and deck seating, letting families regroup without committing to long off-property breaks.

Between meeting suites, on-site catering at select hotels, Wi-Fi, and coffee breaks, agendas remain cohesive while pauses land predictably.

  Call (855) 239-4019 to book with an agent.
  6.8 miles from Center ST. Louis

Starting at

$79.99

per night

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La Quinta Inn & Suites by Wyndham St. Louis Route 66

1580 South Kirkwood Rd St. Louis, Missouri

In Affton, La Quinta Inn & Suites by Wyndham St. Louis Route 66 provides a location that keeps Center ST. Louis within easy reach, letting the stay begin on a positive note.

Reception counters at La Quinta are consistently visible and staffed, reinforcing orientation clarity and dependable arrival routines. Each guest room offers sofa seating, HDTVs, and charging hubs, providing a balance of relaxation, entertainment, and connectivity. Breakfast counters stocked with cereals, fruit, and hot dishes give clarity and stress-free starts to mornings across properties.

Pet-friendly stays, Wi-Fi, and breakfast counters pair with vending and parking, simplifying daily family travel routines.

  Call (855) 239-5277 to book with an agent.
  6.8 miles from Center ST. Louis

Starting at

$103.99

per night

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SpringHill Suites St. Louis Brentwood

1231 Strassner Drive Brentwood, Missouri

When visiting Affton, SpringHill Suites St. Louis Brentwood is located within easy reach of Center ST. Louis, which keeps the main event accessible by vehicle.

With Digital Key access and complimentary Wi-Fi, SpringHill Suites ensures frequent travelers begin smoothly, avoiding friction at arrival. Suites provide lounge seating, work desks, and streaming TVs, creating balanced environments where comfort and productivity coexist naturally. The 24/7 Market carries packaged meals, bottled drinks, and snacks, ensuring guests have access to essentials whenever their schedules demand it.

Amenities such as Wi-Fi, hot breakfast, a fitness facility, and flexible meeting rooms keep both work and leisure routines supported daily.

  Call (855) 239-5277 to book with an agent.
  6.8 miles from Center ST. Louis

Starting at

$136.99

per night

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Holiday Inn St. Louis SW - Route 66 by IHG

10709 Watson Rd St. Louis, Missouri

The hotel's sensible location ensures Center ST. Louis is within easy reach, underscoring its suitability for regional travel.

Lobby bars at Holiday Inn & Suites provide cocktails and lounge seating, giving travelers comfortable hubs to relax after check-in. Suites add lounge seating, sofa beds, and large televisions, supporting families and groups with flexible and comfortable layouts. Pools designed with loungers, towel racks, and family seating create balanced recreation spaces that serve all guest types easily.

Complimentary breakfast, Wi-Fi, and fitness centers combine with self-parking and pools, covering essentials across every property.

  Call (855) 234-5074 to book with an agent.
  7.0 miles from Center ST. Louis

Starting at

$109.99

per night

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TownePlace Suites by Marriott Brentwood

1695 SOUTH HANLEY ROAD Brentwood, Missouri

In Affton, TownePlace Suites by Marriott Brentwood boasts a easy-to-navigate location to Center ST. Louis, letting guests connect with the area before their stay begins.

Lobby décor at TownePlace Suites blends casual seating and soft lighting, producing a welcoming first impression that reassures arrivals. All rooms come equipped with kitchen tools, refrig-storage, and cozy chairs, helping stays flow smoothly between productivity and leisure. Business corner provides workstations and a printer, helping guests stay connected and complete tasks with minimal disruption.

Digital key access, free breakfast, and meeting rooms integrate seamless entry, nourishment, and collaboration for intentional travel days.

  Call (855) 235-6136 to book with an agent.
  7.0 miles from Center ST. Louis

Starting at

$160.99

per night

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Forest Park Hotel by MDR

5915 Wilson Ave St. Louis, Missouri

From Forest Park Hotel by MDR, the easy drive to Center ST. Louis is a core principle of accessibility efficient that defines the beginning of the stay.

Forest Park Hotel by MDR often welcomes arrivals with stylish furnishings, boutique décor, and staff focused on creating a tailored experience. Guest rooms may include curated furnishings, premium bedding, and spa-style bathrooms for a polished boutique-style impression. Amenities often highlight stylish bars, artisanal coffee shops, and curated lounges that reflect boutique character and orientation.

A visit often offers bike rentals, complimentary Wi-Fi, yoga mats, and laundry service, aligning boutique creativity with guest routines.

  Call (855) 235-0725 to book with an agent.
  7.3 miles from Center ST. Louis

Starting at

$79.99

per night

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Red Roof Inn PLUS+ St. Louis - Forest Park / Hampton Ave

5823 Wilson Avenue St. Louis, Missouri

When visiting Center ST. Louis in Affton, the drive from Red Roof Inn PLUS+ St. Louis - Forest Park / Hampton Ave is an easy drive, allowing for a quick return to the hotel.

Red Roof Inn's check-in counters are set up for speed and simplicity, ensuring that guests with reservations can get their keys in hand fast. Each guest room provides abundant lighting options, from bright overhead lights to softer lamps, to suit any mood from working to relaxing. The availability of a business computer removes a point of stress for guests who realize they have a last-minute printing or email need.

A suite of practical amenities like guest laundry, free parking, complimentary Wi-Fi, and free coffee simplifies life on the road.

  Call (855) 234-5074 to book with an agent.
  7.3 miles from Center ST. Louis

Starting at

$71.99

per night

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Courtyard by Marriott St. Louis Brentwood

8101 Dale Avenue Richmond Heights, Missouri

Within Affton, Courtyard by Marriott St. Louis Brentwood keeps Center ST. Louis a simple drive, a fact that lets the hotel to feel both convenient and calm.

Community tables inside Courtyard lobbies provide shared space, encouraging casual conversation before guests head to their rooms. Suites supply sofa seating, large TVs, and dining counters, creating flexible areas for casual meals, work, or family relaxation. In the meeting lounge, ergonomic chairs, projection screens, and flexible layouts ensure productivity during professional events.

Amenities such as Starbucks® coffee, valet parking, meeting spaces, and breakfast spreads reinforce balance across business and leisure.

  Call (855) 235-6136 to book with an agent.
  7.5 miles from Center ST. Louis

Starting at

$161.99

per night

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MainStay Suites St. Louis - Galleria

8011 Galleria Parkway Richmond Heights, Missouri

Within Affton, MainStay Suites St. Louis - Galleria keeps Center ST. Louis an uncomplicated drive, which helps the hotel to feel both convenient and calm.

Adjacent lounge seating at MainStay Suites lets companions relax while check-in completes, so parties remain comfortable and organized nearby. Every room offers a clear workspace, a comfortable chair, and nearby outlets, supporting brief check-ins, homework sessions, or itinerary checks. Meeting suites feature whiteboards, breakout corners, and catering access, helping teams keep momentum between sessions and meals.

Between community lounges, co-working nooks, Wi-Fi, breakfast service, and fitness, guests find both social and productive places on site.

  Call (855) 233-7850 to book with an agent.
  8.1 miles from Center ST. Louis

Starting at

$85.99

per night

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The Cheshire

6300 Clayton Rd Richmond Heights, Missouri

From The Cheshire, Center ST. Louis is a direct run, a choice that makes the entire area feel more accessible.

The Cheshire often highlights a sophisticated reception with elegant seating, concierge guidance, and courteous staff for an upscale welcome. Rooms often highlight refined interiors, premium bedding, and in-room coffee or tea makers that may provide additional guest convenience. Facilities may provide elegant lounges, upscale restaurants, and wellness services that contribute to a sophisticated impression.

A visit may include cocktail bars, wellness spaces, valet service, and Wi-Fi, ensuring refined balance across leisure and convenience.

  Call (855) 235-0725 to book with an agent.
  8.2 miles from Center ST. Louis

Starting at

$141.99

per night

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Homewood Suites by Hilton St. Louis - Galleria

8040 Clayton Road Richmond Heights, Missouri

The benefit of a simple drive to Center ST. Louis turns Homewood Suites by Hilton St. Louis - Galleria into a great starting point before the main on-site experience.

Guests at Homewood Suites can pause at lobby community tables, creating natural spots for relaxed conversation before settling in. Suites feature living areas, dining tables, and sofa seating, creating functional zones for meals, relaxation, or casual work tasks. In the breakfast area, waffles, eggs, and fruit are served, ensuring mornings begin consistently for guests across all locations.

Amenities like outdoor grills, pet-friendly policies, complimentary Wi-Fi, and evening socials give guests flexibility each day.

  Call (855) 234-5074 to book with an agent.
  8.6 miles from Center ST. Louis

Starting at

$162.99

per night

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Hampton Inn & Suites St. Louis at Forest Park

5650 Oakland Avenue St. Louis, Missouri

Upon leaving Hampton Inn & Suites St. Louis at Forest Park, Center ST. Louis is an easy drive, simplifying your visit from the start.

Regional décor and curated finishes in Hampton Inn lobbies reinforce consistent identity, producing polished impressions for arrivals. Each suite includes ergonomic desks, strong Wi-Fi, and charging hubs, creating dependable setups for guests who need productivity on the road. Breakfast rooms with hot buffets, pastries, and self-serve coffee provide dependable clarity, helping mornings start smoothly every day.

On-site markets, complimentary breakfast bags, fitness facilities, Wi-Fi, and outdoor pools deliver convenient balance for guest routines.

  Call (855) 233-7850 to book with an agent.
  8.6 miles from Center ST. Louis

Starting at

$136.99

per night

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Hampton Inn & Suites St. Louis / South I-55

4200 Midamerica Lane St. Louis, Missouri

Reaching Center ST. Louis from Hampton Inn & Suites St. Louis / South I-55 is a simple drive, a quality that enhances the overall guest experience with simplicity.

Hot breakfast stations at Hampton Inn provide variety every morning, supporting daily clarity and dependable routines for travelers. Every guest room features microwaves, refrigerators, and coffee makers, letting travelers prepare snacks and drinks with reliable convenience. Fitness centers with ellipticals, treadmills, and free weights ensure wellness continuity, supporting energy balance while traveling.

Complimentary internet, EV charging, hot breakfast, business centers, and indoor pools provide practical support for modern travel.

  Call (855) 239-4019 to book with an agent.
  8.8 miles from Center ST. Louis

Starting at

$123.99

per night

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Holiday Inn Express & Suites St. Louis South - I-55 by IHG

4250 Midamerica Lane St. Louis, Missouri

The hotel's location is designed for uncomplicated travel, with Center ST. Louis a direct run away, ensuring a confident journey.

Markets near Holiday Inn Express reception desks stock drinks, snacks, and essentials, ensuring guests can access basics conveniently. Guest rooms present branded bath amenities, walk-in showers, and linens, ensuring daily refreshment with predictable comfort. Breakfast setups offering hot dishes, cereals, and fruit deliver clarity for day-start routines across all types of traveling parties.

Pet-friendly policies, complimentary breakfast, and Wi-Fi connect with parking and laundry, ensuring travel routines remain simple.

  Call (855) 233-0132 to book with an agent.
  8.8 miles from Center ST. Louis

Starting at

$124.99

per night

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Fairfield Inn & Suites by Marriott St. Louis South

4318 BUTLER HILL ROAD St. Louis, Missouri

Upon leaving Fairfield Inn & Suites by Marriott St. Louis South, Center ST. Louis is an easy drive with an easy commute, simplifying your visit from the start.

Fairfield Inn arranges work nooks and communal tables in the lobby so brief email checks and map reviews can happen without leaving the property. Each suite integrates ergonomic furniture, reliable Wi-Fi, and charging hubs, creating balanced environments that allow productivity on the go. Fitness areas offer ellipticals, free weights, and mats, allowing guests to sustain wellness routines that keep them energized on the road.

Free Wi-Fi, hot breakfast with eggs and fruit, indoor pool access, and parking options support convenience, helping routines continue daily.

  Call (855) 234-2997 to book with an agent.
  8.9 miles from Center ST. Louis

Starting at

$134.99

per night

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Le Méridien St. Louis Clayton

7730 Bonhomme Ave St. Louis, Missouri

The uncomplicated drive from Le Méridien St. Louis Clayton to Center ST. Louis in Affton means the commute is truly efficient before the stay unfolds.

Guests entering Le Méridien encounter clear signage, concierge desks, and modular seating, details that simplify orientation and comfort. Every suite supplies curated minibars, bright lighting, and hardwood flooring, reinforcing European-inspired luxury and reliability. Guests visiting the rooftop bar enjoy crafted cocktails, skyline views, and lounge seating, premium spaces for relaxation and social ease.

With breakfast spreads, cultural lounges, outdoor seating, and wellness spas, guests experience reliable amenities with daily ease.

  Call (855) 236-8982 to book with an agent.
  9.5 miles from Center ST. Louis

Starting at

$195.99

per night

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The Ritz-Carlton St. Louis

100 Carondelet Plaza St. Louis, Missouri

For travelers with a car-based itinerary, The Ritz-Carlton St. Louis offers an easy drive to Center ST. Louis, making it a smart anchor for exploring the region.

At Club Level, Ritz-Carlton welcomes guests with concierge-led check-in, offering privacy and clarity for travelers seeking premium service. Suites feature walk-in showers, deep tubs, and premium bath amenities, letting travelers unwind and restore balance after full days. Bars curate wine lists, classic cocktails, and attentive service, offering a simple evening reset after conferences or city outings.

With espresso bars, lobby lounges, and rooftop terraces alongside Wi-Fi, guests move seamlessly from work catch-ups to casual evenings.

  Call (855) 233-0132 to book with an agent.
  9.7 miles from Center ST. Louis

Starting at

$539.99

per night

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Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis, Missouri

From Clayton Plaza Hotel & Extended Stay, Center ST. Louis is a direct run, a feature that enhances the feeling of being well-situated.

By welcoming pets, Extended Stay America caters to the needs of a wide range of travelers, from families to solo workers. All suites are furnished with the necessary dishes, glasses, and silverware, removing a common hassle for extended-stay hotel guests. A clean and well-maintained swimming pool is a delightful feature for any traveler looking for a little relaxation during their stay.

A guest-focused approach includes a swimming pool, guest laundry, a full kitchen in every room, and a complimentary grab-and-go breakfast.

  Call (855) 236-8982 to book with an agent.
  9.7 miles from Center ST. Louis

Starting at

$108.99

per night

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Home2 Suites by Hilton St. Louis / Forest Park

920 South Taylor Avenue St. Louis, Missouri

In Affton, Home2 Suites by Hilton St. Louis / Forest Park provides a location that keeps Center ST. Louis a simple drive, letting the stay begin on a positive note.

Guests in Home2 Suites lobbies encounter community tables and colorful seating, creating casual areas that encourage conversation. Every suite delivers refrigerators, utensils, and dishwashers, supporting families with convenient meal preparation daily. The Home2 Market supplies snacks, drinks, and travel necessities, ensuring guests have 24/7 convenience that simplifies extended stays.

Amenities such as pools, fitness centers, Wi-Fi, and pet-friendly policies ensure routines remain consistent across every visit.

  Call (855) 234-5074 to book with an agent.
  9.8 miles from Center ST. Louis

Starting at

$175.99

per night

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The Knight Center at Washington University

Throop Dr. and Snow Way St. Louis, Missouri

The hotel's location is a smart choice, keeping Center ST. Louis within easy reach and contributing to a controlled itinerary.

At The Knight Center at Washington University, arrivals may present straightforward check-in, available parking, and simple lobby furnishings for guest use. Each guest room may include hardwood finishes, compact seating, and rainfall showers, creating a practical yet stylish stay setting. Facilities often provide vending access, compact breakfast areas, and laundry spaces that maintain clarity and reliability for guests.

A visit may feature Wi-Fi, compact breakfast counters, vending machines, and laundry access, supporting daily travel balance reliably.

  Call (855) 235-0725 to book with an agent.
  9.9 miles from Center ST. Louis

Starting at

$169.99

per night

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