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Top 24 Hotels Near Isle Casino Cape Girardeau
777 Main St Cape Girardeau, MO 63701



The Riverview

777 Main St Cape Girardeau, Missouri

The defining relationship between The Riverview and Isle Casino Cape Girardeau is proximity, as they are right beside, streamlining the guest journey.

At The Riverview, guests may encounter stylish interiors, courteous staff, and luggage service that highlight an upscale arrival. Rooms often highlight elegant design details, upscale bedding, and spa-style bathrooms that enhance a refined and comfortable experience. Property amenities often offer stylish bars, full-service dining, and wellness spaces designed to enhance a luxury-focused impression.

A stay may highlight plush bedding, wellness services, cocktail lounges, and Wi-Fi, blending modern convenience with refined indulgence.

  Call (855) 234-5074 to book with an agent.
  0.0 miles from Isle Casino Cape Girardeau

Starting at

$114.99

per night

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Courtyard by Marriott Cape Girardeau Downtown

400 Broadway St. Cape Girardeau, Missouri

The benefit of a brief trip to Isle Casino Cape Girardeau makes Courtyard by Marriott Cape Girardeau Downtown into a starting point for a day of easy transitions.

Guests at Courtyard find Digital Key prompts near reception, letting loyalty members bypass delays and begin their stays faster. Each guest room delivers blackout curtains, plush bedding, and climate control, helping ensure restful conditions across stays. At the Market, sandwiches, bottled water, and grab-and-go items offer dependable options that help maintain routines every day.

Guests benefit from free Wi-Fi, valet parking, breakfast buffets, and fitness centers, ensuring travel feels seamless and reliable.

  Call (855) 236-8982 to book with an agent.
  0.9 miles from Isle Casino Cape Girardeau

Starting at

$134.99

per night

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Rockwood Inn

603 Henderson Ave Cape Girardeau, Missouri

The hotel's location is designed for efficient travel, with Isle Casino Cape Girardeau a short drive away, ensuring guests can maximize their time.

Guests at Rockwood Inn may encounter a simple desk, quick parking options, and vending access arranged for reliable budget arrivals. Accommodations may include plush bedding, climate control, and streaming access, offering both comfort and entertainment for visitors. Shared spaces may include modest lobbies, vending corners, and breakfast rooms that provide practical places for guests to gather daily.

A stay often highlights Wi-Fi, vending areas, modest breakfast, and guest laundries, helping sustain clear routines for daily visitors.

  Call (855) 233-7850 to book with an agent.
  1.4 miles from Isle Casino Cape Girardeau

Starting at

$165.99

per night

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Town House Inn Cape Giradreau

505 North Kingshighway Street Cape Girardeau, Missouri

This easy commute to Isle Casino Cape Girardeau permits Town House Inn Cape Giradreau to be a peaceful yet connected base before the on-site experience.

Town House Inn Cape Giradreau typically offers efficient check-in, modest lobby chairs, and self-serve coffee that emphasize budget-style convenience. Rooms may feature hardwood floors, curated décor, and compact seating, delivering a modest yet comfortable base for overnight stays. Facilities often highlight guest laundries, compact business nooks, and vending areas that support simple routines while traveling.

Accommodations may present Wi-Fi, vending machines, breakfast service, and laundry rooms, maintaining practical balance in budget hotels.

  Call (855) 234-7135 to book with an agent.
  3.2 miles from Isle Casino Cape Girardeau

Starting at

$55.00

per night

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Hampton Inn Cape Girardeau I 55 East

207 South Mt. Auburn Rd Cape Girardeau, Missouri

Because Hampton Inn Cape Girardeau I 55 East keeps Isle Casino Cape Girardeau a direct run, guests can opt on the travel method that best suits their needs.

Bright lighting and open layouts at Hampton Inn receptions support orientation clarity, giving travelers smooth navigation cues at check-in. All guest rooms feature blackout curtains, quiet HVAC, and plush mattresses, ensuring every night ends with restorative and consistent rest. Lobby lounges with coffee service, sofa clusters, and regional décor foster relaxed atmospheres that encourage guest connection.

EV charging, complimentary Wi-Fi, indoor pools, breakfast bags, and laundry access support daily routines with flexible convenience.

  Call (855) 239-4019 to book with an agent.
  5.4 miles from Isle Casino Cape Girardeau

Starting at

$115.99

per night

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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau, Missouri

In Cape Girardeau, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG is situated a simple cross-town drive from Isle Casino Cape Girardeau, a position that fosters a sense of calm.

Lobby designs at Holiday Inn Express emphasize symmetry and bright lighting, easing orientation and providing dependable comfort. All guest rooms provide flat-screen TVs, plush beds, and blackout curtains, making restful sleep and easy relaxation predictable. Pools furnished with towel racks, seating, and umbrellas deliver recreational balance for families and individual travelers.

Free Wi-Fi, hot breakfast, and laundry facilities pair with pools and parking, providing predictability for longer visits.

  Call (855) 234-5074 to book with an agent.
  5.5 miles from Isle Casino Cape Girardeau

Starting at

$118.99

per night

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Candlewood Suites Cape Girardeau by IHG

485 South Mount Auburn Rd Cape Girardeau, Missouri

From Candlewood Suites Cape Girardeau by IHG, Isle Casino Cape Girardeau is a direct run, offering a straightforward route for getting to your destination.

Desk placement at Candlewood Suites aligns with elevator sightlines, reducing detours when several arrivals reach check-in together. Every suite includes dish soap, towels, and starter paper goods, letting first meals and cleanups proceed without extra errands. Pool areas, where present, post depth markers, handrails, and towel return, supporting calm cooldowns and tidy transitions back to rooms.

With a business center, scanners, and printers plus Wi-Fi and coffee, packets and agendas finalize without off-site errands.

  Call (855) 235-0725 to book with an agent.
  5.6 miles from Isle Casino Cape Girardeau

Starting at

$90.99

per night

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Fairfield Inn & Suites by Marriott Cape Girardeau

433 CAPE WEST CROSSINGS Cape Girardeau, Missouri

Reaching Isle Casino Cape Girardeau from Fairfield Inn & Suites by Marriott Cape Girardeau is a simple drive, a feature that weaves ease into the start of any day.

To reduce decision friction, Fairfield Inn places menu boards and market displays beside the desk so food and drink choices can be scanned fast. Guest rooms highlight flat-screen TVs, lounge seating, and cable access, creating personal retreat areas for travelers to relax comfortably. Breakfast sections highlight hot items, cereals, and baked goods, giving families consistent choices to keep mornings structured and clear.

Amenities like business centers, complimentary Wi-Fi, hot breakfast, and market access give travelers the dependable support they expect daily.

  Call (855) 239-4019 to book with an agent.
  5.6 miles from Isle Casino Cape Girardeau

Starting at

$114.99

per night

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Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau, Missouri

Reaching Isle Casino Cape Girardeau from Quality Inn Cape Girardeau North is a simple drive, a trait that weaves simplicity into the guest's daily routine.

Quality Inn layouts limit cross-traffic by routing doors, elevators, and desk areas into clear lines that suit families and solo travelers. Suites present flexible layouts with sofa beds, extra seating, and storage to accommodate families or overflow guests without crowding bedrooms. Breakfast counters place grab-and-go items beside coffee taps so early travelers fuel up quickly and keep tight morning itineraries on track.

Business support desks and meeting suites pair with dependable Wi-Fi so last-minute slides, prints, and boarding passes are handled on site.

  Call (855) 233-7850 to book with an agent.
  6.3 miles from Isle Casino Cape Girardeau

Starting at

$61.99

per night

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Tru by Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau, Missouri

For guests in Cape Girardeau, Tru by Hilton Cape Girardeau keeps Isle Casino Cape Girardeau within easy reach, a spot that makes for a graceful start to any day.

With a focus on value and a spirited welcome, Tru by Hilton ensures that your arrival experience is both positive and memorable. Guests visiting the fitness center use cardio machines, resistance gear, and mats, ensuring consistency in daily wellness routines. Guests enjoying the Hive lobby encounter colorful seating, casual games, and bright accents, producing first impressions of energy.

With Top It breakfast, 24/7 markets, Wi-Fi, and parking, guests find simple comforts that help make daily travel smooth and easy.

  Call (855) 233-0132 to book with an agent.
  8.3 miles from Isle Casino Cape Girardeau

Starting at

$106.99

per night

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Comfort Suites Jackson-Cape Girardeau

2904 Old Orchard Rd Jackson, Missouri

From Comfort Suites Jackson-Cape Girardeau, the direct commute provides access to Isle Casino Cape Girardeau, enhancing the stay.

At check-in Comfort Suites places staffed front desks and nearby seating so arriving travelers regroup easily while keys and room details are prepared. Each guest room supplies complimentary Wi-Fi and a streaming-ready TV, keeping remote work, calls, and entertainment connected without fuss. Lobby markets and vending corners stock snacks, bottled drinks, and travel essentials so late arrivals avoid off-site convenience trips.

Between Wi-Fi, streaming-ready TVs, and charging hubs, entertainment and remote calls stay connected without extra setup in suites.

  Call (855) 235-0725 to book with an agent.
  9.5 miles from Isle Casino Cape Girardeau

Starting at

$79.99

per night

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La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau

3003 SOUTH OLD ORCHARD ROAD Jackson, Missouri

At La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau, Isle Casino Cape Girardeau is an uncomplicated drive for event attendees, enhancing the visit.

La Quinta offers loyalty members digital check-in via the Wyndham Rewards app, reducing wait times and creating smoother arrivals. All guest rooms emphasize ergonomic desks, supportive seating, and strong Wi-Fi, enabling travelers to remain productive daily. Lobby areas incorporating communal tables, natural light, and lounge chairs deliver regrouping spaces and orientation clarity.

Free Wi-Fi, self-parking, and breakfast counters align with fitness centers and vending, maintaining balance and ease for guests.

  Call (855) 233-0132 to book with an agent.
  9.5 miles from Isle Casino Cape Girardeau

Starting at

$85.99

per night

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Town House Inn

517 East Jackson Blvd Jackson, Missouri

Isle Casino Cape Girardeau is an easy regional drive from Town House Inn, a plan that ensures travel plans are always straightforward.

Arrivals at Town House Inn may highlight basic reception, complimentary parking, and vending machines for guest-oriented practicality. Each guest room typically offers premium bedding, blackout curtains, and climate control, ensuring consistency and rest throughout stays. Public areas may include breakfast spaces, coin-operated laundries, and seating corners that emphasize straightforward convenience.

A visit may offer Wi-Fi, guest laundry, vending corners, and compact breakfast areas, sustaining clarity for everyday guest routines.

  Call (855) 234-2997 to book with an agent.
  14.7 miles from Isle Casino Cape Girardeau

Starting at

$65.99

per night

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Hotel 7 Inn Anna

100 Richview Dr Anna, Illinois

This practical base helps Hotel 7 Inn Anna guests get acquainted with the local Cape Girardeau area without a long drive.

Hotel 7 Inn Anna often provides no-frills check-in, nearby parking, and modest lobby seating that reinforce straightforward travel flow. Guest rooms often include ergonomic chairs, compact desks, and Wi-Fi, supporting guests who balance work and relaxation while away. Shared spaces typically feature modest lobbies, vending machines, and laundry rooms that help guests maintain routines on the road.

Guests may encounter Wi-Fi, modest breakfast, vending access, and parking, reflecting straightforward support across budget properties.

  Call (855) 234-5074 to book with an agent.
  30.7 miles from Isle Casino Cape Girardeau

Starting at

$88.40

per night

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EC Reeds Mercantile and Hotel

301 1st St Marble Hill, Missouri

For a trip to the area, EC Reeds Mercantile and Hotel's location as a convenient base is an essential aspect of its appeal.

Guests at EC Reeds Mercantile and Hotel may find artisanal touches, intimate décor, and complimentary coffee or tea for a welcoming boutique start. Accommodations may include curated furnishings, spa-style bathrooms, and plush bedding that create a boutique guest impression. Shared spaces may feature curated art, intimate bars, and eclectic seating areas that emphasize boutique individuality and style.

Guests may enjoy artisanal breakfast, self-serve markets, Wi-Fi, and laundry facilities, ensuring flexibility for longer boutique visits.

  Call (855) 234-5074 to book with an agent.
  41.1 miles from Isle Casino Cape Girardeau

Starting at

$87.99

per night

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Quality Inn Cairo I-57

13201 Kessler Road Cairo, Illinois

Because Quality Inn Cairo I-57 is a practical base, guests can opt to start their day with a moment of quiet reflection.

At check-in Quality Inn front-desk teams make luggage storage and early-check options visible so guests can explore light while rooms are readied. Guest rooms combine a streaming-ready TV, reliable Wi-Fi, and easy casting so entertainment and remote meetings start without setup. Guest vending corners and market shelves provide batteries, toiletries, and snacks so travelers avoid late-night trips off property during stays.

Pool decks, shaded loungers, and family swim sections give uncomplicated downtime options so guests recover between travel or event blocks.

  Call (855) 233-7850 to book with an agent.
  41.5 miles from Isle Casino Cape Girardeau

Starting at

$81.99

per night

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Country Yard Inn and Suite

110 South Interstate Drive Sikeston, Missouri

This convenient location allows Country Yard Inn and Suite to offer a convenient and well-integrated lodging experience with Isle Casino Cape Girardeau within driving reach.

At Country Yard Inn and Suite, arrivals may showcase compact desks, vending services, and on-site parking designed for consistent guest arrivals. Guest rooms may highlight plush bedding, curated décor, and climate control, ensuring comfort and balance across overnight routines. Facilities may present breakfast areas, guest laundries, and small seating zones that reflect the practical focus of budget properties.

A stay often provides Wi-Fi, vending machines, laundry facilities, and breakfast counters, reinforcing reliable balance each day.

  Call (855) 235-0725 to book with an agent.
  46.7 miles from Isle Casino Cape Girardeau

Starting at

$50.99

per night

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Best Western Plus Sikeston

120 South Interstate Drive Sikeston, Missouri

From Best Western Plus Sikeston, the easy regional drive to Isle Casino Cape Girardeau is a core benefit for a grounded visit before the day begins.

Best Western posts concise neighborhood guides and QR links by the desk, turning first questions into direct routes for dining and transit options. Guest rooms, with medium-firm mattresses, blackout shades, and quiet HVAC, steady sleep so mornings begin clear and better paced. Fitness centers combine treadmills, bikes, and free weights with towels and water, helping routines stay intact across back-to-back travel days.

From dining lounges where present, Wi-Fi, fitness access, and parking, evenings combine unwind and logistics without losing next-day focus.

  Call (855) 233-0132 to book with an agent.
  46.8 miles from Isle Casino Cape Girardeau

Starting at

$62.99

per night

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Super 8 by Wyndham Charleston / Sikeston East MO

310 South Story St Charleston, Missouri

Upon arrival at Super 8 by Wyndham Charleston / Sikeston East MO, Isle Casino Cape Girardeau is a simple commute, simplifying your visit.

Murals and bold design elements in Super 8 lobbies reflect the brand’s modern refresh, creating memorable yet functional first looks. All guest rooms supply plush mattresses, blackout curtains, and crisp linens, delivering restorative sleep and reliable comfort nightly. Breakfast areas serving cereals, pastries, and hot dishes help families and professionals maintain clarity in morning routines.

Pet-friendly rooms, complimentary breakfast, and Wi-Fi pair with parking and vending, offering clarity and consistency for families.

  Call (855) 234-5074 to book with an agent.
  46.9 miles from Isle Casino Cape Girardeau

Starting at

$59.99

per night

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Super 8 by Wyndham Sikeston / Miner Area

2609 East Malone Ave Sikeston, Missouri

As a convenient base, Super 8 by Wyndham Sikeston / Miner Area is a key element that supports a flexible and relaxed visit.

Super 8 offers complimentary tea and coffee throughout the day, reinforcing attention to care and easing transitions after long drives. Suites come with sofa beds, larger layouts, and lounge seating, giving families dependable flexibility and comfort across stays. Fitness rooms at select properties with treadmills, weights, and stretching zones keep exercise routines intact while traveling.

Connectivity with Wi-Fi, breakfast buffets, and laundry combines with parking and business corners, simplifying daily traveler needs.

  Call (855) 234-2997 to book with an agent.
  46.9 miles from Isle Casino Cape Girardeau

Starting at

$58.99

per night

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Travel Inn & Suites - Sikeston / Miner (i-55 Exit-67)

100 Matthews Lane Sikeston, Missouri

Because Travel Inn & Suites - Sikeston / Miner (i-55 Exit-67) is a convenient base, guests can enjoy a moment of quiet before driving to Isle Casino Cape Girardeau.

Guests at Travel Inn & Suites - Sikeston / Miner (i-55 Exit-67) may encounter efficient front desk help, simple seating, and complimentary parking for predictable routines. Accommodations often include hardwood accents, compact seating, and rainfall showers, providing a modern yet approachable guest stay. Amenities may include vending corners, guest laundries, and compact breakfast rooms that sustain consistent daily routines for travelers.

Accommodations may include Wi-Fi, breakfast areas, vending access, and guest laundries, sustaining simple routines for all travelers.

  Call (855) 234-2997 to book with an agent.
  47.0 miles from Isle Casino Cape Girardeau

Starting at

$55.99

per night

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Comfort Inn & Suites Sikeston I-55

109 Matthews Ln Sikeston, Missouri

The hotel's spot as a practical base gives Comfort Inn & Suites Sikeston I-55 guests a easy way to transition into their day of travel.

With bell service or staff assistance, Comfort Inn helps manage luggage handoffs so arriving travelers can proceed without hassle. All guest rooms combine blackout treatments and quiet room profiles to limit light and noise, improving rest before busy days ahead. Lobby seating zones place charging ports and small tables so companions can plan routes or check itineraries while waiting at the desk.

With meeting rooms, AV support, event parking, Wi-Fi, and catering, small conferences and trainings are handled comfortably on site.

  Call (855) 239-4019 to book with an agent.
  47.0 miles from Isle Casino Cape Girardeau

Starting at

$92.99

per night

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Days Inn and Suites by Wyndham Sikeston

220 South Interstate Dr Sikeston, Missouri

This practical role as a base makes Days Inn and Suites by Wyndham Sikeston a core hub for those visiting Isle Casino Cape Girardeau from out of town.

With bright lobby lighting and clear glazing, Days Inn keeps visibility high from sidewalk to counter, easing wayfinding after dark. Every guest room leaves clear floor space around the bed and entry, easing luggage movement and late returns without clutter or noise. Wayfinding pairs icon signage with room-range boards at elevator banks, making routes to markets, restrooms, and meeting rooms direct.

In one loop, market coolers, packaged meals, and utensils plus microwaves and Wi-Fi make casual dining come together without a drive.

  Call (855) 233-0132 to book with an agent.
  47.1 miles from Isle Casino Cape Girardeau

Starting at

$65.99

per night

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Eagle Inn Charleston

2811 East Marshall Street Charleston, Missouri

This convenient location means Eagle Inn Charleston is a practical base with Isle Casino Cape Girardeau an easy drive away.

Eagle Inn Charleston typically includes modest reception service, vending access, and parking close to entry points for stress-free arrivals. Rooms may feature premium linens, blackout curtains, and in-room coffee, supporting both rest and routine refreshment during travel. Shared spaces often provide modest lobbies, vending machines, and breakfast counters that support clarity and comfort during stays.

A visit may highlight Wi-Fi, compact breakfast service, vending machines, and parking, giving guests consistent ease while traveling.

  Call (855) 234-5074 to book with an agent.
  47.2 miles from Isle Casino Cape Girardeau

Starting at

$60.49

per night

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